Sail into the Heart of the Americas – Central & South America Cruises 2025, 2026 & 2027
Uncover the rich culture, vibrant cities, and dramatic landscapes of Central and South America on a cruise adventure like no other. Our Central & South America cruises for 2025, 2026, and 2027 take you from the tropical beaches of Costa Rica and Panama to the awe-inspiring fjords of Chile and the passionate rhythms of Brazil and Argentina. Whether you're transiting the iconic Panama Canal, exploring ancient Incan ruins, or witnessing the wildlife of the Amazon, these cruises combine discovery with comfort and style.
Plan your unforgettable voyage now — book early for the best cabins and exclusive early bird offers.
Looking for inspiration also see out Central & South America cruise destination pages.
Central & South America Cruise Deals - Frequently Asked Questions
Cruises often include ports in Mexico, Costa Rica, Panama (including the Panama Canal), Colombia, Brazil, Argentina, Chile, Peru, and Uruguay. Some itineraries may also explore Antarctica or the Galápagos Islands.
The best time varies by region, but generally:
- Central America: November to April (dry season)
- South America (Brazil, Argentina, Chile): December to March
- Amazon River: Best from July to December for low water and easier wildlife spotting
Cruises typically range from 10 to 21 nights, depending on the route. Panama Canal transits and longer South America itineraries can extend to 30 nights or more.
Find A South America Cruise
Explore our wide selection of Central & South America cruises below. Use the filters to find the perfect itinerary that matches your travel dates and preferences.